Melanoma antigen recognized by T-cells 1

BE0010469ProteinHumansMLANA

Involved in melanosome biogenesis by ensuring the stability of GPR143. It is acted on by 1 drug in DrugBank.

Gene name
MLANA
UniProtKB entry
Q16655Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
118 residues · 13,157 Da
Also known as
Antigen LB39-AA · Antigen SK29-AA · MART-1 · MART1 · Protein Melan-A

Resolves to

Protein
UniProtQ16655UniProt nameMAR1_HUMAN
Gene
HGNCHGNC:7124NCBI Gene2315GeneCardsMLANA
Pharmacology
KEGGhsa:2315
Structure
PDB2GT9PDB2GTWPDB2GTZ
Drugs

What you can answer from here — as of October 31, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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39Clinical trialsTrials of drugs acting on it, by phase and status
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Melanoma antigen recognized by T-cells 1, and which indications are they being tested in?

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