Delta-like protein 4

BE0010485ProteinHumansDLL4

Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954). It is acted on by 4 drugs in DrugBank.

Gene name
DLL4
UniProtKB entry
Q9NR61Swiss-Prot
Cellular location
Cell membrane
Residues / weight
685 residues · 74,604 Da
Also known as
Delta4 · Drosophila Delta homolog 4

Resolves to

Protein
UniProtQ9NR61UniProt nameDLL4_HUMAN
Gene
HGNCHGNC:2910NCBI Gene54567GeneCardsDLL4
Pharmacology
KEGGhsa:54567
Structure
PDB5MVX
Drugs

What you can answer from here — as of October 31, 2023

4DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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31GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Delta-like protein 4, and which indications are they being tested in?

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