Interleukin-1 receptor accessory protein

BE0010488ProteinHumansIL1RAP

Coreceptor for IL1RL2 in the IL-36 signaling system (By similarity). It is acted on by 1 drug in DrugBank.

Gene name
IL1RAP
UniProtKB entry
Q9NPH3Swiss-Prot
Cellular location
Cell membrane
Residues / weight
570 residues · 65,418 Da
Also known as
3.2.2.6 · C3orf13 · IL-1 receptor accessory protein · IL-1R-3 · IL-1R3

Resolves to

Protein
UniProtQ9NPH3UniProt nameIL1AP_HUMAN
Gene
HGNCHGNC:5995NCBI Gene3556GeneCardsIL1RAP
Pharmacology
IUPHAR/GtoPdb1897KEGGhsa:3556
Structure
PDB3O4OPDB4DEPPDB7FCC
Drugs

What you can answer from here — as of October 31, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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15GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Interleukin-1 receptor accessory protein, and which indications are they being tested in?

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