Proepiregulin

BE0010495ProteinHumansEREG

Ligand of the EGF receptor/EGFR and ERBB4. It is acted on by 1 drug in DrugBank.

Gene name
EREG
UniProtKB entry
O14944Swiss-Prot
Cellular location
Secreted, extracellular space
Residues / weight
169 residues · 19,044 Da

Resolves to

Protein
UniProtO14944UniProt nameEREG_HUMAN
Gene
HGNCHGNC:3443NCBI Gene2069GeneCardsEREG
Pharmacology
KEGGhsa:2069
Structure
PDB1K36PDB1K37PDB5E8D
Drugs

What you can answer from here — as of October 31, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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4Clinical trialsTrials of drugs acting on it, by phase and status
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Proepiregulin, and which indications are they being tested in?

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