Clathrin heavy chain 1

BE0010500ProteinHumansCLTC

Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. It is acted on by 1 drug in DrugBank.

Gene name
CLTC
UniProtKB entry
Q00610Swiss-Prot
Cellular location
Cytoplasmic vesicle membrane
Residues / weight
1,675 residues · 191,613 Da
Also known as
Clathrin heavy chain on chromosome 17 · CLH-17 · CLH17 · CLTCL2 · KIAA0034

Resolves to

Protein
UniProtQ00610UniProt nameCLH1_HUMAN
Gene
HGNCHGNC:2092NCBI Gene1213GeneCardsCLTC
Pharmacology
KEGGhsa:1213
Structure
PDB2XZGPDB4G55PDB6E4L
Drugs

What you can answer from here — as of October 31, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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43GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Clathrin heavy chain 1, and which indications are they being tested in?

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