5,6-dihydroxyindole-2-carboxylic acid oxidase

BE0010503ProteinHumansTYRP1

Plays a role in melanin biosynthesis (PubMed:16704458, PubMed:22556244, PubMed:23504663). It is acted on by 2 drugs in DrugBank.

Gene name
TYRP1
UniProtKB entry
P17643Swiss-Prot
Cellular location
Melanosome membrane
Residues / weight
537 residues · 60,724 Da
Also known as
1.14.18.- · CAS2 · Catalase B · DHICA oxidase · Glycoprotein 75

Resolves to

Protein
UniProtP17643UniProt nameTYRP1_HUMAN
Gene
HGNCHGNC:12450NCBI Gene7306GeneCardsTYRP1
Pharmacology
KEGGhsa:7306
Structure
PDB5M8LPDB5M8MPDB5M8N
Drugs

What you can answer from here — as of October 31, 2023

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 5,6-dihydroxyindole-2-carboxylic acid oxidase, and which indications are they being tested in?

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