Proto-oncogene vav

BE0010510ProteinHumansVAV1

Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation. It is acted on by 1 drug in DrugBank.

Gene name
VAV1
UniProtKB entry
P15498Swiss-Prot
Residues / weight
845 residues · 98,313 Da
Also known as
VAV

Resolves to

Protein
UniProtP15498UniProt nameVAV_HUMAN
Gene
HGNCHGNC:12657NCBI Gene7409GeneCardsVAV1
Pharmacology
KEGGhsa:7409
Structure
PDB2CRHPDB2LCTPDB2MC1
Drugs

What you can answer from here — as of October 31, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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6GO termsFunction, process and component, as structured annotations
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6Pfam domainsDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Proto-oncogene vav, and which indications are they being tested in?

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