Progonadoliberin-1

BE0010526ProteinHumansGNRH1

Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones. It is acted on by 2 drugs in DrugBank.

Gene name
GNRH1
UniProtKB entry
P01148Swiss-Prot
Cellular location
Secreted
Residues / weight
92 residues · 10,380 Da
Also known as
GNRH · GRH · LHRH · Progonadoliberin I

Resolves to

Protein
UniProtP01148UniProt nameGON1_HUMAN
Gene
HGNCHGNC:4419NCBI Gene2796GeneCardsGNRH1
Pharmacology
KEGGhsa:2796
Structure
PDB4D5MPDB9U4W
Drugs

What you can answer from here — as of October 31, 2023

2DrugsApproved to experimental, with action, bond type and pharmacological action
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3Clinical trialsTrials of drugs acting on it, by phase and status
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23GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Progonadoliberin-1, how selective are they, and which programs against it are still in active trials?

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