Progonadoliberin-1

Details

Name
Progonadoliberin-1
Kind
protein
Synonyms
  • GNRH
  • GRH
  • LHRH
  • Progonadoliberin I
Gene Name
GNRH1
UniProtKB Entry
P01148Swiss-Prot
Organism
Humans
NCBI Taxonomy ID
9606
Amino acid sequence
>lcl|BSEQ0053339|Progonadoliberin-1
MKPIQKLLAGLILLTWCVEGCSSQHWSYGLRPGGKRDAENLIDSFQEIVKEVGQLAETQR
FECTTHQPRSPLRDLKGALESLIEEETGQKKI
Number of residues
92
Molecular Weight
10379.835
Theoretical pI
Not Available
GO Classification
Not Available
General Function
Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones
Specific Function
gonadotropin hormone-releasing hormone activity
Pfam Domain Function
Signal Regions
1-23
Transmembrane Regions
Not Available
Cellular Location
Secreted
Gene sequence
>lcl|BSEQ0053340|Progonadoliberin-1 (GNRH1)
ATGAAGCCAATTCAAAAACTCCTAGCTGGCCTTATTCTACTGACTTGGTGCGTGGAAGGC
TGCTCCAGCCAGCACTGGTCCTATGGACTGCGCCCTGGAGGAAAGAGAGATGCCGAAAAT
TTGATTGATTCTTTCCAAGAGATAGTCAAAGAGGTTGGTCAACTGGCAGAAACCCAACGC
TTCGAATGCACCACGCACCAGCCACGTTCTCCCCTCCGAGACCTGAAAGGAGCTCTGGAA
AGTCTGATTGAAGAGGAAACTGGGCAGAAGAAGATTTAA
Chromosome Location
8
Locus
8p21.2
External Identifiers
ResourceLink
UniProtKB IDP01148
UniProtKB Entry NameGON1_HUMAN
GeneCard IDGNRH1
HGNC IDHGNC:4419
PDB ID(s)4D5M
KEGG IDhsa:2796
NCBI Gene ID2796
General References
Not Available

Associated Data

Drug Relations
DrugDrug groupPharmacological action?TypeActionsDetails
Leuprolideapproved, investigationalyestargetactivatorDetails
GoserelinapprovedyestargetactivatorDetails