Glypican-3

BE0010527ProteinHumansGPC3

Cell surface proteoglycan (PubMed:14610063). It is acted on by 2 drugs in DrugBank.

Gene name
GPC3
UniProtKB entry
P51654Swiss-Prot
Cellular location
Cell membrane
Residues / weight
580 residues · 65,562 Da
Also known as
GTR2-2 · Intestinal protein OCI-5 · MXR7 · OCI5

Resolves to

Protein
UniProtP51654UniProt nameGPC3_HUMAN
Gene
HGNCHGNC:4451NCBI Gene2719GeneCardsGPC3
Pharmacology
KEGGhsa:2719
Structure
PDB7ZA1PDB7ZAWPDB9NTQ
Drugs

What you can answer from here — as of October 31, 2023

2DrugsApproved to experimental, with action, bond type and pharmacological action
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9Clinical trialsTrials of drugs acting on it, by phase and status
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Glypican-3, and which indications are they being tested in?

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