Melanoma-associated antigen 4

BE0010534ProteinHumansMAGEA4

Regulates cell proliferation through the inhibition of cell cycle arrest at the G1 phase (PubMed:22842486). It is acted on by 1 drug in DrugBank.

Gene name
MAGEA4
UniProtKB entry
P43358Swiss-Prot
Residues / weight
317 residues · 34,899 Da
Also known as
Cancer/testis antigen 1.4 · CT1.4 · MAGE-4 antigen · MAGE-41 antigen · MAGE-X2 antigen

Resolves to

Protein
UniProtP43358UniProt nameMAGA4_HUMAN
Gene
HGNCHGNC:6802NCBI Gene4103GeneCardsMAGEA4
Pharmacology
KEGGhsa:4103
Structure
PDB1I4FPDB2WA0PDB6TRN
Drugs

What you can answer from here — as of October 31, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Melanoma-associated antigen 4, how selective are they, and which programs against it are still in active trials?

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