Hepatitis A virus cellular receptor 2

BE0010551ProteinHumansHAVCR2

Cell surface receptor implicated in modulating innate and adaptive immune responses. It is acted on by 6 drugs in DrugBank.

Gene name
HAVCR2
UniProtKB entry
Q8TDQ0Swiss-Prot
Cellular location
Cell membrane
Residues / weight
301 residues · 33,394 Da
Also known as
HAVcr-2 · T-cell immunoglobulin and mucin domain-containing protein 3 · T-cell immunoglobulin mucin receptor 3 · T-cell membrane protein 3 · TIM-3

Resolves to

Protein
UniProtQ8TDQ0UniProt nameHAVR2_HUMAN
Gene
HGNCHGNC:18437NCBI Gene84868GeneCardsHAVCR2
Pharmacology
IUPHAR/GtoPdb2940KEGGhsa:84868
Structure
PDB5DZLPDB5F71PDB6DHB
Drugs

What you can answer from here — as of October 31, 2023

6DrugsApproved to experimental, with action, bond type and pharmacological action
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11Clinical trialsTrials of drugs acting on it, by phase and status
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42GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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17+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Hepatitis A virus cellular receptor 2, and which indications are they being tested in?

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