NKG2-A/NKG2-B type II integral membrane protein

BE0010560ProteinHumansKLRC1

Immune inhibitory receptor involved in self-nonself discrimination. It is acted on by 1 drug in DrugBank.

Gene name
KLRC1
UniProtKB entry
P26715Swiss-Prot
Cellular location
Cell membrane
Residues / weight
233 residues · 26,314 Da
Also known as
CD159 antigen-like family member A · NK cell receptor A · NKG2-A/B-activating NK receptor · NKG2A

Resolves to

Protein
UniProtP26715UniProt nameNKG2A_HUMAN
Gene
HGNCHGNC:6374NCBI Gene3821GeneCardsKLRC1
Pharmacology
IUPHAR/GtoPdb2849KEGGhsa:3821
Structure
PDB2RMXPDB2YU7PDB3BDW
Drugs

What you can answer from here — as of October 31, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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12GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on NKG2-A/NKG2-B type II integral membrane protein, and which indications are they being tested in?

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