Lymphocyte function-associated antigen 3

BE0010569ProteinHumansCD58

Ligand of the T-lymphocyte CD2 glycoprotein. It is acted on by 1 drug in DrugBank.

Gene name
CD58
UniProtKB entry
P19256Swiss-Prot
Cellular location
Cell membrane
Residues / weight
250 residues · 28,147 Da
Also known as
Ag3 · LFA3 · Surface glycoprotein LFA-3

Resolves to

Protein
UniProtP19256UniProt nameLFA3_HUMAN
Gene
HGNCHGNC:1688NCBI Gene965GeneCardsCD58
Pharmacology
KEGGhsa:965
Structure
PDB1CCZPDB1CI5PDB1QA9
Drugs

What you can answer from here — as of October 31, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which approved drugs act on Lymphocyte function-associated antigen 3, how selective are they, and which programs against it are still in active trials?

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