Indian hedgehog protein

BE0010596ProteinHumansIHH

Precursor of indian hedgehog, a morphogen that activates the smoothened signaling pathway, and which is essential for bone and cartilage development (By similarity). It is acted on by 2 drugs in DrugBank.

Gene name
IHH
UniProtKB entry
Q14623Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
411 residues · 45,250 Da
Also known as
3.1.-.- · HHG-2 · IHH

Resolves to

Protein
UniProtQ14623UniProt nameIHH_HUMAN
Gene
HGNCHGNC:5956NCBI Gene3549GeneCardsIHH
Pharmacology
KEGGhsa:3549
Structure
PDB3K7GPDB3K7HPDB3K7I
Drugs

What you can answer from here — as of October 31, 2023

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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4GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Indian hedgehog protein, and which indications are they being tested in?

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