Tyrosine-protein phosphatase non-receptor type substrate 1

BE0010650ProteinHumansSIRPA

Immunoglobulin-like cell surface receptor for CD47. It is acted on by 2 drugs in DrugBank.

Gene name
SIRPA
UniProtKB entry
P78324Swiss-Prot
Cellular location
Membrane
Residues / weight
504 residues · 54,966 Da
Also known as
BIT · Brain Ig-like molecule with tyrosine-based activation motifs · CD172 antigen-like family member A · Inhibitory receptor SHPS-1 · Macrophage fusion receptor

Resolves to

Protein
UniProtP78324UniProt nameSHPS1_HUMAN
Gene
HGNCHGNC:9662NCBI Gene140885GeneCardsSIRPA
Pharmacology
KEGGhsa:140885
Structure
PDB2JJSPDB2JJTPDB2UV3
Drugs

What you can answer from here — as of October 31, 2023

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
1Clinical trialTrials of drugs acting on it, by phase and status
Sign in
4GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
3+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Tyrosine-protein phosphatase non-receptor type substrate 1, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In