Killer cell immunoglobulin-like receptor 2DL3

BE0010665ProteinHumansKIR2DL3

Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). It is acted on by 2 drugs in DrugBank.

Gene name
KIR2DL3
UniProtKB entry
P43628Swiss-Prot
Cellular location
Cell membrane
Residues / weight
341 residues · 37,886 Da
Also known as
CD158 antigen-like family member B2 · CD158B2 · Killer inhibitory receptor cl 2-3 · KIR-023GB · KIRCL23

Resolves to

Protein
UniProtP43628UniProt nameKI2L3_HUMAN
Gene
HGNCHGNC:6331NCBI Gene3804GeneCardsKIR2DL3
Pharmacology
KEGGhsa:3804
Structure
PDB1B6UPDB6PAGPDB8TUI
Drugs

What you can answer from here — as of October 31, 2023

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Killer cell immunoglobulin-like receptor 2DL3, and which indications are they being tested in?

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