Semaphorin-4D

BE0010680ProteinHumansSEMA4D

Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling (PubMed:20877282). It is acted on by 1 drug in DrugBank.

Gene name
SEMA4D
UniProtKB entry
Q92854Swiss-Prot
Cellular location
Cell membrane
Residues / weight
862 residues · 96,149 Da
Also known as
A8 · BB18 · C9orf164 · CD100 · GR3

Resolves to

Protein
UniProtQ92854UniProt nameSEM4D_HUMAN
Gene
HGNCHGNC:10732NCBI Gene10507GeneCardsSEMA4D
Pharmacology
IUPHAR/GtoPdb2883KEGGhsa:10507
Structure
PDB1OLZPDB3OL2
Drugs

What you can answer from here — as of October 31, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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4Clinical trialsTrials of drugs acting on it, by phase and status
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9GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Semaphorin-4D, and which indications are they being tested in?

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