Ribonuclease P protein subunit p21

BE0010712ProteinHumansRPP21

Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. It is acted on by 1 drug in DrugBank.

Gene name
RPP21
UniProtKB entry
Q9H633Swiss-Prot
Cellular location
Nucleus, nucleolus
Residues / weight
154 residues · 17,570 Da
Also known as
C6orf135 · CAT60 · Ribonuclease P/MRP 21 kDa subunit · Ribonucleoprotein V · RNaseP protein p21

Resolves to

Protein
UniProtQ9H633UniProt nameRPP21_HUMAN
Gene
HGNCHGNC:21300NCBI Gene79897GeneCardsRPP21
Pharmacology
KEGGhsa:79897
Structure
PDB6AHRPDB6AHU
Drugs

What you can answer from here — as of October 31, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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8Clinical trialsTrials of drugs acting on it, by phase and status
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Ribonuclease P protein subunit p21, and which indications are they being tested in?

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