Ubiquitin-conjugating enzyme E2 C

BE0010756ProteinHumansUBE2C

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. It is acted on by 1 drug in DrugBank.

Gene name
UBE2C
UniProtKB entry
O00762Swiss-Prot
Residues / weight
179 residues · 19,652 Da
Also known as
(E3-independent) E2 ubiquitin-conjugating enzyme C · 2.3.2.23 · E2 ubiquitin-conjugating enzyme C · UBCH10 · Ubiquitin carrier protein C

Resolves to

Protein
UniProtO00762UniProt nameUBE2C_HUMAN
Gene
HGNCHGNC:15937NCBI Gene11065GeneCardsUBE2C
Pharmacology
KEGGhsa:11065
Structure
PDB1I7KPDB4YIIPDB5A31
Drugs

What you can answer from here — as of October 31, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Ubiquitin-conjugating enzyme E2 C, and which indications are they being tested in?

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