Myelin basic protein

BE0010777ProteinHumansMBP

The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. It is acted on by 2 drugs in DrugBank.

Gene name
MBP
UniProtKB entry
P02686Swiss-Prot
Cellular location
Myelin membrane
Residues / weight
304 residues · 33,117 Da
Also known as
MBP · Myelin A1 protein · Myelin membrane encephalitogenic protein

Resolves to

Protein
UniProtP02686UniProt nameMBP_HUMAN
Gene
HGNCHGNC:6925NCBI Gene4155GeneCardsMBP
Pharmacology
KEGGhsa:4155
Structure
PDB1BX2PDB1FV1PDB1HQR
Drugs

What you can answer from here — as of October 31, 2023

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Myelin basic protein, and which indications are they being tested in?

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