Interleukin-27 subunit alpha

BE0010791ProteinHumansIL27

Associates with EBI3 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. It is acted on by 1 drug in DrugBank.

Gene name
IL27
UniProtKB entry
Q8NEV9Swiss-Prot
Cellular location
Secreted
Residues / weight
243 residues · 27,493 Da
Also known as
IL-27 subunit alpha · IL-27-A · IL27-A · IL27A · IL30

Resolves to

Protein
UniProtQ8NEV9UniProt nameIL27A_HUMAN
Gene
HGNCHGNC:19157NCBI Gene246778GeneCardsIL27
Pharmacology
KEGGhsa:246778
Structure
PDB7U7NPDB7ZXKPDB8D85
Drugs

What you can answer from here — as of October 31, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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6GO termsFunction, process and component, as structured annotations
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Interleukin-27 subunit alpha, and which indications are they being tested in?

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