Trans-acting T-cell-specific transcription factor GATA-3

BE0010794ProteinHumansGATA3

Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. It is acted on by 1 drug in DrugBank.

Gene name
GATA3
UniProtKB entry
P23771Swiss-Prot
Cellular location
Nucleus
Residues / weight
443 residues · 47,916 Da
Also known as
GATA-binding factor 3

Resolves to

Protein
UniProtP23771UniProt nameGATA3_HUMAN
Gene
HGNCHGNC:4172NCBI Gene2625GeneCardsGATA3
Pharmacology
KEGGhsa:2625
Structure
PDB4HC7PDB4HC9PDB4HCA
Drugs

What you can answer from here — as of October 31, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
1Clinical trialTrials of drugs acting on it, by phase and status
Sign in
10GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
1+ReferenceStructured and connected to the statements they support
Sign in

Which approved drugs act on Trans-acting T-cell-specific transcription factor GATA-3, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In