Inactive tyrosine-protein kinase transmembrane receptor ROR1

BE0010828ProteinHumansROR1

Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo (PubMed:25029443). It is acted on by 2 drugs in DrugBank.

Gene name
ROR1
UniProtKB entry
Q01973Swiss-Prot
Cellular location
Cell membrane
Residues / weight
937 residues · 104,282 Da
Also known as
Neurotrophic tyrosine kinase, receptor-related 1 · NTRKR1

Resolves to

Protein
UniProtQ01973UniProt nameROR1_HUMAN
Gene
HGNCHGNC:10256NCBI Gene4919GeneCardsROR1
Pharmacology
KEGGhsa:4919
Structure
PDB5Z55PDB6BA5PDB6BAN
Drugs

What you can answer from here — as of October 31, 2023

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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9GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Inactive tyrosine-protein kinase transmembrane receptor ROR1, and which indications are they being tested in?

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