Killer cell immunoglobulin-like receptor 2DL2

BE0010848ProteinHumansKIR2DL2

Receptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. It is acted on by 2 drugs in DrugBank.

Gene name
KIR2DL2
UniProtKB entry
P43627Swiss-Prot
Cellular location
Cell membrane
Residues / weight
348 residues · 38,472 Da
Also known as
CD158 antigen-like family member B1 · CD158B1 · Natural killer-associated transcript 6 · NKAT-6 · NKAT6

Resolves to

Protein
UniProtP43627UniProt nameKI2L2_HUMAN
Gene
HGNCHGNC:6330NCBI Gene3803GeneCardsKIR2DL2
Pharmacology
KEGGhsa:3803
Structure
PDB1EFXPDB2DL2PDB2DLI
Drugs

What you can answer from here — as of October 31, 2023

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Killer cell immunoglobulin-like receptor 2DL2, and which indications are they being tested in?

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