Glycogen debranching enzyme

BE0010883ProteinHumansAGL

Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation. It is acted on by 1 drug in DrugBank.

Gene name
AGL
UniProtKB entry
P35573Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
1,532 residues · 174,762 Da
Also known as
GDE · Glycogen debrancher

Resolves to

Protein
UniProtP35573UniProt nameGDE_HUMAN
Gene
HGNCHGNC:321NCBI Gene178GeneCardsAGL
Pharmacology
KEGGhsa:178
Structure
PDB8ZEQ
Drugs

What you can answer from here — as of October 31, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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2GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which approved drugs act on Glycogen debranching enzyme, how selective are they, and which programs against it are still in active trials?

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