65 kDa phosphoprotein

BE0010916ProteinHHV-5UL83

Counteracts the host antiviral immune response when activated and phosphorylated, by preventing host IRF3 from entering the nucleus (PubMed:15452220). It is acted on by 3 drugs in DrugBank.

Gene name
UL83
UniProtKB entry
P06725Swiss-Prot
Cellular location
Virion tegument
Residues / weight
561 residues · 62,898 Da
Also known as
65 kDa matrix phosphoprotein · Phosphoprotein UL83 · pp65 · Tegument protein UL83

Resolves to

Protein
UniProtP06725UniProt namePP65_HCMVA
Structure
PDB2X4RPDB2X4TPDB3GSO
Drugs

What you can answer from here — as of November 01, 2023

3DrugsApproved to experimental, with action, bond type and pharmacological action
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3Clinical trialsTrials of drugs acting on it, by phase and status
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 65 kDa phosphoprotein, and which indications are they being tested in?

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