Protein Rev

BE0010935ProteinHuman immunodeficiency virus type 1 group M subtype B (isolate HXB2)rev

Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells. It is acted on by 1 drug in DrugBank.

Gene name
rev
UniProtKB entry
P04618Swiss-Prot
Cellular location
Host nucleus
Residues / weight
116 residues · 13,075 Da
Also known as
Anti-repression transactivator · ART/TRS · Regulator of expression of viral proteins

Resolves to

Protein
UniProtP04618UniProt nameREV_HV1H2
Gene
NCBI Gene155908
Pharmacology
KEGGvg:155908
Structure
PDB6HIPPDB7JYA
Drugs

What you can answer from here — as of November 01, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Protein Rev, and which indications are they being tested in?

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