RAC-alpha serine/threonine-protein kinase

BE0010936ProteinMouseAkt1

AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis (PubMed:11882383, PubMed:21432781, PubMed:21620960, PubMed:26095253, PubMed:26107252,... It is acted on by 1 drug in DrugBank.

Gene name
Akt1
UniProtKB entry
P31750Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
480 residues · 55,707 Da
Also known as
2.7.11.1 · Akt · AKT1 kinase · PKB · PKB alpha

Resolves to

Protein
UniProtP31750UniProt nameAKT1_MOUSE
Gene
NCBI Gene11651
Pharmacology
KEGGmmu:11651
Drugs

What you can answer from here — as of November 01, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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175GO termsFunction, process and component, as structured annotations
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on RAC-alpha serine/threonine-protein kinase, and which indications are they being tested in?

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