Macrophage scavenger receptor types I and II

BE0010942ProteinHumansMSR1

Membrane receptor that mediates the binding, endocytosis and phagocytosis of a broad range of ligands. It is acted on by 2 drugs in DrugBank.

Gene name
MSR1
UniProtKB entry
P21757Swiss-Prot
Cellular location
Cell membrane
Residues / weight
451 residues · 49,762 Da
Also known as
Macrophage acetylated LDL receptor I and II · SCARA1 · Scavenger receptor class A member 1

Resolves to

Protein
UniProtP21757UniProt nameMSRE_HUMAN
Gene
HGNCHGNC:7376NCBI Gene4481GeneCardsMSR1
Pharmacology
KEGGhsa:4481
Structure
PDB7DPX
Drugs

What you can answer from here — as of November 16, 2023

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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15GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Macrophage scavenger receptor types I and II, how selective are they, and which programs against it are still in active trials?

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