Chloride channel protein 1

BE0010943ProteinHumansCLCN1

Voltage-gated chloride channel involved in skeletal muscle excitability. It is acted on by 1 drug in DrugBank.

Gene name
CLCN1
UniProtKB entry
P35523Swiss-Prot
Cellular location
Cell membrane
Residues / weight
988 residues · 108,625 Da
Also known as
Chloride channel protein, skeletal muscle · ClC-1 · CLC1

Resolves to

Protein
UniProtP35523UniProt nameCLCN1_HUMAN
Gene
HGNCHGNC:2019NCBI Gene1180GeneCardsCLCN1
Pharmacology
IUPHAR/GtoPdb698KEGGhsa:1180
Structure
PDB6COYPDB6COZPDB6QV6
Drugs

What you can answer from here — as of November 16, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Chloride channel protein 1, and which indications are they being tested in?

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