External core antigen

BE0010950ProteinHepatitis B virus genotype D subtype ayw (isolate France/Tiollais/1979)C

May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells. It is acted on by 1 drug in DrugBank.

Gene name
C
UniProtKB entry
P0C573Swiss-Prot
Cellular location
Secreted
Residues / weight
212 residues · 24,350 Da
Also known as
HBeAg · p25 · Precore protein

Resolves to

Protein
UniProtP0C573UniProt nameHBEAG_HBVD3
Drugs

What you can answer from here — as of November 16, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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32Clinical trialsTrials of drugs acting on it, by phase and status
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11GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on External core antigen, and which indications are they being tested in?

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