Tumor necrosis factor ligand superfamily member 15

BE0010966ProteinHumansTNFSF15

Cytokine that signals through TNFRSF25 receptor (PubMed:11911831). It is acted on by 3 drugs in DrugBank.

Gene name
TNFSF15
UniProtKB entry
O95150Swiss-Prot
Cellular location
Membrane
Residues / weight
251 residues · 28,087 Da
Also known as
TL1 · TL1A · TNF ligand-related molecule 1 · Vascular endothelial cell growth inhibitor · VEGI

Resolves to

Protein
UniProtO95150UniProt nameTNF15_HUMAN
Gene
HGNCHGNC:11931NCBI Gene9966GeneCardsTNFSF15
Pharmacology
KEGGhsa:9966
Structure
PDB2O0OPDB2QE3PDB2RE9
Drugs

What you can answer from here — as of March 25, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Tumor necrosis factor ligand superfamily member 15, and which indications are they being tested in?

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