Molybdenum cofactor biosynthesis protein 1

BE0011005ProteinHumansMOCS1

Isoform MOCS1A and isoform MOCS1B probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP) (PubMed:11891227, PubMed:23627491, PubMed:29368224, PubMed:31996372). It is acted on by 1 drug in DrugBank.

Gene name
MOCS1
UniProtKB entry
Q9NZB8Swiss-Prot
Cellular location
Mitochondrion matrix
Residues / weight
636 residues · 70,104 Da
Also known as
Cell migration-inducing gene 11 protein · Molybdenum cofactor synthesis-step 1 protein A-B

Resolves to

Protein
UniProtQ9NZB8UniProt nameMOCS1_HUMAN
Gene
HGNCHGNC:7190NCBI Gene4337GeneCardsMOCS1
Pharmacology
KEGGhsa:4337
Drugs

What you can answer from here — as of July 26, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Molybdenum cofactor biosynthesis protein 1, how selective are they, and which programs against it are still in active trials?

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