5'-AMP-activated protein kinase catalytic subunit alpha-2

BE0011007ProteinRatPrkaa2

Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism (PubMed:14511394).

Gene name
Prkaa2
UniProtKB entry
Q09137Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
552 residues · 62,257 Da
Also known as
2.7.11.1 · ACACA kinase · Acetyl-CoA carboxylase kinase · Ampk · AMPK subunit alpha-2

Resolves to

Protein
UniProtQ09137UniProt nameAAPK2_RAT
Gene
NCBI Gene78975
Pharmacology
KEGGrno:78975

What you can answer from here — as of July 31, 2024

61GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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Which compounds in development act on 5'-AMP-activated protein kinase catalytic subunit alpha-2, and which indications are they being tested in?

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