Beta-mannosidase

BE0011383ProteinHumansMANBA

Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides. It is acted on by 1 drug in DrugBank.

Gene name
MANBA
UniProtKB entry
O00462Swiss-Prot
Cellular location
Lysosome
Residues / weight
879 residues · 100,894 Da
Also known as
3.2.1.25 · Lysosomal beta A mannosidase · MANB1 · Mannanase · Mannase

Resolves to

Protein
UniProtO00462UniProt nameMANBA_HUMAN
Gene
HGNCHGNC:6831NCBI Gene4126GeneCardsMANBA
Pharmacology
KEGGhsa:4126
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Beta-mannosidase, and which indications are they being tested in?

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