Prosaposin receptor GPR37

BE0011479ProteinHumansGPR37

G protein-coupled receptor that plays a role in several physiological pathways such as resolution of inflammatory pain and oligodendrocyte differentiation (By similarity). It is acted on by 1 drug in DrugBank.

Gene name
GPR37
UniProtKB entry
O15354Swiss-Prot
Cellular location
Cell projection, dendrite
Residues / weight
613 residues · 67,113 Da
Also known as
Endothelin B receptor-like protein 1 · ETBR-LP-1 · G protein-coupled receptor 37 · PAELR · Parkin-associated endothelin receptor-like receptor

Resolves to

Protein
UniProtO15354UniProt nameGPR37_HUMAN
Gene
HGNCHGNC:4494NCBI Gene2861GeneCardsGPR37
Pharmacology
IUPHAR/GtoPdb103KEGGhsa:2861
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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25GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Prosaposin receptor GPR37, and which indications are they being tested in?

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