Centrosomal protein of 290 kDa

BE0011534ProteinHumansCEP290

Involved in early and late steps in cilia formation. It is acted on by 2 drugs in DrugBank.

Gene name
CEP290
UniProtKB entry
O15078Swiss-Prot
Cellular location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Residues / weight
2,479 residues · 290,384 Da
Also known as
Bardet-Biedl syndrome 14 protein · BBS14 · Cancer/testis antigen 87 · Cep290 · CT87

Resolves to

Protein
UniProtO15078UniProt nameCE290_HUMAN
Gene
HGNCHGNC:29021NCBI Gene80184GeneCardsCEP290
Pharmacology
KEGGhsa:80184
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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30GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Centrosomal protein of 290 kDa, and which indications are they being tested in?

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