Sphingolipid delta(4)-desaturase DES1

BE0011584ProteinHumansDEGS1

Has sphingolipid-delta-4-desaturase activity. It is acted on by 1 drug in DrugBank.

Gene name
DEGS1
UniProtKB entry
O15121Swiss-Prot
Cellular location
Mitochondrion membrane
Residues / weight
323 residues · 37,866 Da
Also known as
1.14.19.17 · Cell migration-inducing gene 15 protein · Degenerative spermatocyte homolog 1 · DES1 · Dihydroceramide desaturase-1

Resolves to

Protein
UniProtO15121UniProt nameDEGS1_HUMAN
Gene
HGNCHGNC:13709NCBI Gene8560GeneCardsDEGS1
Pharmacology
IUPHAR/GtoPdb2484KEGGhsa:8560
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Sphingolipid delta(4)-desaturase DES1, and which indications are they being tested in?

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