T-box transcription factor T

BE0011656ProteinHumansTBXT

Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. It is acted on by 1 drug in DrugBank.

Gene name
TBXT
UniProtKB entry
O15178Swiss-Prot
Cellular location
Nucleus
Residues / weight
435 residues · 47,443 Da
Also known as
Brachyury protein · Protein T · T

Resolves to

Protein
UniProtO15178UniProt nameTBXT_HUMAN
Gene
HGNCHGNC:11515NCBI Gene6862GeneCardsTBXT
Pharmacology
IUPHAR/GtoPdb3304KEGGhsa:6862
Structure
PDB5QRFPDB5QRGPDB5QRH
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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20GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on T-box transcription factor T, and which indications are they being tested in?

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