Glucose-6-phosphate exchanger SLC37A4

BE0011751ProteinHumansSLC37A4

Inorganic phosphate and glucose-6-phosphate antiporter of the endoplasmic reticulum (PubMed:10026167, PubMed:21949678). It is acted on by 1 drug in DrugBank.

Gene name
SLC37A4
UniProtKB entry
O43826Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
429 residues · 46,360 Da
Also known as
G6PT · G6PT1 · Glucose-6-phosphate translocase · Glucose-6-phosphate transporter · Solute carrier family 37 member 4

Resolves to

Protein
UniProtO43826UniProt nameG6PT1_HUMAN
Gene
HGNCHGNC:4061NCBI Gene2542GeneCardsSLC37A4
Pharmacology
KEGGhsa:2542
Structure
PDB9KUYPDB9KV0PDB9KVV
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Glucose-6-phosphate exchanger SLC37A4, and which indications are they being tested in?

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