Toll-like receptor 5

BE0011820ProteinHumansTLR5

Pattern recognition receptor (PRR) located on the cell surface that participates in the activation of innate immunity and inflammatory response (PubMed:11323673, PubMed:18490781). It is acted on by 3 drugs in DrugBank.

Gene name
TLR5
UniProtKB entry
O60602Swiss-Prot
Cellular location
Cell membrane
Residues / weight
858 residues · 97,798 Da
Also known as
TIL3 · Toll/interleukin-1 receptor-like protein 3

Resolves to

Protein
UniProtO60602UniProt nameTLR5_HUMAN
Gene
HGNCHGNC:11851NCBI Gene7100GeneCardsTLR5
Pharmacology
KEGGhsa:7100
Structure
PDB3J0APDB8AR2
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
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11GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Toll-like receptor 5, and which indications are they being tested in?

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