Aquaporin-8

BE0011894ProteinHumansAQP8

Channel that allows the facilitated permeation of water and uncharged molecules, such as hydrogen peroxide and the neutral form of ammonia (NH3), through cellular membranes such as plasma membrane, inner mitochondrial membrane and endoplasmic reticulum... It is acted on by 2 drugs in DrugBank.

Gene name
AQP8
UniProtKB entry
O94778Swiss-Prot
Cellular location
Cell membrane
Residues / weight
261 residues · 27,381 Da
Also known as
AQP-8

Resolves to

Protein
UniProtO94778UniProt nameAQP8_HUMAN
Gene
HGNCHGNC:642NCBI Gene343GeneCardsAQP8
Pharmacology
KEGGhsa:343
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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27GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Aquaporin-8, how selective are they, and which programs against it are still in active trials?

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