Bis(monoacylglycero)phosphate synthase CLN5

BE0011971ProteinHumansCLN5

Catalyzes the synthesis of bis(monoacylglycero)phosphate (BMP) via transacylation of 2 molecules of lysophosphatidylglycerol (LPG) (PubMed:37708259). It is acted on by 1 drug in DrugBank.

Gene name
CLN5
UniProtKB entry
O75503Swiss-Prot
Cellular location
Lysosome
Residues / weight
358 residues · 41,496 Da
Also known as
2.3.1.- · BMP synthase CLN5 · BMPS · Ceroid-lipofuscinosis neuronal protein 5 · Palmitoyl protein thioesterase CLN5

Resolves to

Protein
UniProtO75503UniProt nameCLN5_HUMAN
Gene
HGNCHGNC:2076NCBI Gene1203GeneCardsCLN5
Pharmacology
KEGGhsa:1203
Structure
PDB6R99
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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23GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Bis(monoacylglycero)phosphate synthase CLN5, and which indications are they being tested in?

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