F-box-like/WD repeat-containing protein TBL1X

BE0012106ProteinHumansTBL1X

F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units (PubMed:14980219). It is acted on by 1 drug in DrugBank.

Gene name
TBL1X
UniProtKB entry
O60907Swiss-Prot
Cellular location
Nucleus
Residues / weight
577 residues · 62,495 Da
Also known as
SMAP55 · TBL1 · Transducin beta-like protein 1X · Transducin-beta-like protein 1, X-linked

Resolves to

Protein
UniProtO60907UniProt nameTBL1X_HUMAN
Gene
HGNCHGNC:11585NCBI Gene6907GeneCardsTBL1X
Pharmacology
KEGGhsa:6907
Structure
PDB2XTCPDB2XTDPDB2XTE
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
18GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
1+ReferenceStructured and connected to the statements they support
Sign in

Which compounds in development act on F-box-like/WD repeat-containing protein TBL1X, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In