Claudin-1

BE0012196ProteinHumansCLDN1

Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. It is acted on by 1 drug in DrugBank.

Gene name
CLDN1
UniProtKB entry
O95832Swiss-Prot
Cellular location
Cell junction, tight junction
Residues / weight
211 residues · 22,744 Da
Also known as
CLD1 · SEMP1 · Senescence-associated epithelial membrane protein

Resolves to

Protein
UniProtO95832UniProt nameCLD1_HUMAN
Gene
HGNCHGNC:2032NCBI Gene9076GeneCardsCLDN1
Pharmacology
KEGGhsa:9076
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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37GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Claudin-1, and which indications are they being tested in?

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