Polymeric immunoglobulin receptor

BE0012259ProteinHumansPIGR

Mediates selective transcytosis of polymeric IgA and IgM across mucosal epithelial cells. It is acted on by 1 drug in DrugBank.

Gene name
PIGR
UniProtKB entry
P01833Swiss-Prot
Cellular location
Cell membrane
Residues / weight
764 residues · 83,283 Da
Also known as
Hepatocellular carcinoma-associated protein TB6 · PIgR · Poly-Ig receptor

Resolves to

Protein
UniProtP01833UniProt namePIGR_HUMAN
Gene
HGNCHGNC:8968NCBI Gene5284GeneCardsPIGR
Pharmacology
KEGGhsa:5284
Structure
PDB1XEDPDB2OCWPDB3CHN
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which approved drugs act on Polymeric immunoglobulin receptor, how selective are they, and which programs against it are still in active trials?

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