Zinc finger and BTB domain-containing protein 7A

BE0012406ProteinHumansZBTB7A

Transcription factor that represses the transcription of a wide range of genes involved in cell proliferation and differentiation (PubMed:14701838, PubMed:17595526, PubMed:20812024, PubMed:25514493, PubMed:26455326, PubMed:26816381). It is acted on by 1 drug in DrugBank.

Gene name
ZBTB7A
UniProtKB entry
O95365Swiss-Prot
Cellular location
Nucleus
Residues / weight
584 residues · 61,439 Da
Also known as
Factor binding IST protein 1 · Factor that binds to inducer of short transcripts protein 1 · FBI-1 · FBI1 · HIV-1 1st-binding protein 1

Resolves to

Protein
UniProtO95365UniProt nameZBT7A_HUMAN
Gene
HGNCHGNC:18078NCBI Gene51341GeneCardsZBTB7A
Pharmacology
IUPHAR/GtoPdb3327KEGGhsa:51341
Structure
PDB2IF5PDB2NN2PDB7EYI
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Zinc finger and BTB domain-containing protein 7A, and which indications are they being tested in?

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