Amino acid transporter heavy chain SLC3A2

BE0012576ProteinHumansSLC3A2

Acts as a chaperone that facilitates biogenesis and trafficking of functional transporter heterodimers to the plasma membrane. It is acted on by 1 drug in DrugBank.

Gene name
SLC3A2
UniProtKB entry
P08195Swiss-Prot
Cellular location
Apical cell membrane
Residues / weight
529 residues · 57,944 Da
Also known as
4F2 cell-surface antigen heavy chain · 4F2 heavy chain antigen · 4F2hc · Lymphocyte activation antigen 4F2 large subunit · MDU1

Resolves to

Protein
UniProtP08195UniProt name4F2_HUMAN
Gene
HGNCHGNC:11026NCBI Gene6520GeneCardsSLC3A2
Pharmacology
IUPHAR/GtoPdb890KEGGhsa:6520
Structure
PDB2DH2PDB2DH3PDB6IRS
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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43GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Amino acid transporter heavy chain SLC3A2, and which indications are they being tested in?

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