High mobility group protein HMG-I/HMG-Y

BE0012648ProteinHumansHMGA1

HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is acted on by 1 drug in DrugBank.

Gene name
HMGA1
UniProtKB entry
P17096Swiss-Prot
Cellular location
Nucleus
Residues / weight
107 residues · 11,676 Da
Also known as
High mobility group AT-hook protein 1 · High mobility group protein A1 · High mobility group protein R · HMG-I(Y) · HMGIY

Resolves to

Protein
UniProtP17096UniProt nameHMGA1_HUMAN
Gene
HGNCHGNC:5010NCBI Gene3159GeneCardsHMGA1
Pharmacology
KEGGhsa:3159
Structure
PDB2EZDPDB2EZEPDB2EZF
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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35GO termsFunction, process and component, as structured annotations
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on High mobility group protein HMG-I/HMG-Y, and which indications are they being tested in?

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