Beta-galactoside alpha-2,6-sialyltransferase 1

BE0012689ProteinHumansST6GAL1

Transfers sialic acid from CMP-sialic acid to galactose-containing acceptor substrates. It is acted on by 2 drugs in DrugBank.

Gene name
ST6GAL1
UniProtKB entry
P15907Swiss-Prot
Cellular location
Golgi apparatus, Golgi stack membrane
Residues / weight
406 residues · 46,604 Da
Also known as
2.4.3.1 · Alpha 2,6-ST 1 · CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1 · Sialyltransferase 1 · SIAT1

Resolves to

Protein
UniProtP15907UniProt nameSIAT1_HUMAN
Gene
HGNCHGNC:10860NCBI Gene6480GeneCardsST6GAL1
Pharmacology
KEGGhsa:6480
Structure
PDB4JS1PDB4JS2PDB6QVS
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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12GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Beta-galactoside alpha-2,6-sialyltransferase 1, and which indications are they being tested in?

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